Pharmacist Salary

Columbia vs Spartanburg: Pharmacist Salary (2026)

Compare pharmacist salaries between Columbia, SC and Spartanburg, SC. All figures are 2026 estimates projected from BLS 2025 data.

Columbia, SC
$136,299
$65.53/hr
Spartanburg, SC
$156,421
$75.20/hr

Side-by-Side Comparison

MetricColumbia, SCSpartanburg, SC
Median Salary$136,299$156,421
Hourly Rate$65.53$75.20
Entry Level (P10)$82,879$87,564
25th Percentile$116,606$134,334
75th Percentile$155,393$174,516
Top Earner (P90)$172,643$174,516
Total Employed1,050480
Side-by-side bar chart comparing Columbia ($136,299) and Spartanburg ($156,421) pharmacist salaries.ColumbiaSpartanburgMedian Salary$136,299$156,421Entry Level (P10)$82,879$87,564Top Earner (P90)$172,643$174,516US Median $143,489

Verdict

Spartanburg, SC offers better overall compensation for pharmacists, winning 3 out of 4 metrics compared to Columbia.

The salary gap between Columbia and Spartanburg is $20,122 (14.76%). Spartanburg's median is +9.01% compared to the US national median of $143,489.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Columbia spans $89,764,Spartanburg spans $86,952. Columbia has a wider pay range, meaning more potential for high earners but also more variation.

Columbia
P10 (Entry)$82,879
P25$116,606
Median$136,299
P75$155,393
P90 (Top)$172,643
Spartanburg
P10 (Entry)$87,564
P25$134,334
Median$156,421
P75$174,516
P90 (Top)$174,516

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Spartanburg ($171,795 effective) pays 18.05% more than Columbia ($145,522 effective).

Columbia
Nominal: $136,299
CoL Index: 93.662
Adjusted: $145,522
Spartanburg
Nominal: $156,421
CoL Index: 91.051
Adjusted: $171,795

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Columbia if…

  • Larger job market (1,050 employed)
  • You prefer the South Carolina area and lifestyle

Choose Spartanburg if…

  • Higher median salary ($156,421/year)
  • Better top-earner potential ($174,516)
  • Better purchasing power (CoL-adjusted: $171,795)
  • You prefer the South Carolina area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, pharmacist salaries in Columbia grew 12.7% from 2019 to 2025, compared to 19.6% growth in Spartanburg over the same period.

Columbia, SC

+12.7%

$118,730 (2019) → $133,850 (2025)

Spartanburg, SC

+19.6%

$128,410 (2019) → $153,610 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays pharmacists more: Columbia or Spartanburg?

Spartanburg has a higher median pharmacist salary at $156,421/year, compared to Columbia at $136,299/year — a difference of $20,122 (14.76%).

What is the hourly rate difference between Columbia and Spartanburg?

Columbia pharmacists earn $65.53/hr while Spartanburg hygienists earn $75.20/hr (2026 est.).

Should I relocate from Columbia to Spartanburg as a pharmacist?

Consider more than just salary when comparing Columbia and Spartanburg. Factor in cost of living (CoL-adjusted: Columbia = $145,522, Spartanburg = $171,795), job availability (1,050 vs 480 employed), commute, and career growth potential.

What do entry-level pharmacists earn in Columbia vs Spartanburg?

Entry-level (10th percentile) pharmacists earn $82,879 in Columbia and $87,564 in Spartanburg. The Spartanburg area offers higher starting salaries.
SC

Written by Sofia Chen, PharmD

Career Analyst

Sofia Chen has 10 years of experience in community pharmacy. She specializes in medication therapy management.

Clinically reviewed by Liam Patel, PharmDData verified by Amina Al-Sayed, PharmD

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 1.83% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Sofia Chen, PharmD, a licensed pharmacist with 10+ years of clinical experience. · View source data at BLS.gov