Pharmacist Salary

San Antonio vs Tyler: Pharmacist Salary (2026)

Compare pharmacist salaries between San Antonio, TX and Tyler, TX. All figures are 2026 estimates projected from BLS 2025 data.

San Antonio, TX
$153,254
$73.68/hr
Tyler, TX
$139,293
$66.96/hr

Side-by-Side Comparison

MetricSan Antonio, TXTyler, TX
Median Salary$153,254$139,293
Hourly Rate$73.68$66.96
Entry Level (P10)$98,439$106,311
25th Percentile$135,383$130,556
75th Percentile$161,777$155,902
Top Earner (P90)$170,158$161,543
Total Employed2,260280
Side-by-side bar chart comparing San Antonio ($153,254) and Tyler ($139,293) pharmacist salaries.San AntonioTylerMedian Salary$153,254$139,293Entry Level (P10)$98,439$106,311Top Earner (P90)$170,158$161,543US Median $143,489

Verdict

San Antonio, TX offers better overall compensation for pharmacists, winning 4 out of 4 metrics compared to Tyler.

The salary gap between San Antonio and Tyler is $13,961 (10.02%). San Antonio's median is +6.81% compared to the US national median of $143,489.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Antonio spans $71,719,Tyler spans $55,232. San Antonio has a wider pay range, meaning more potential for high earners but also more variation.

San Antonio
P10 (Entry)$98,439
P25$135,383
Median$153,254
P75$161,777
P90 (Top)$170,158
Tyler
P10 (Entry)$106,311
P25$130,556
Median$139,293
P75$155,902
P90 (Top)$161,543

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Antonio ($161,804 effective) pays 7.05% more than Tyler ($151,149 effective).

San Antonio
Nominal: $153,254
CoL Index: 94.716
Adjusted: $161,804
Tyler
Nominal: $139,293
CoL Index: 92.156
Adjusted: $151,149

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Antonio if…

  • Higher median salary ($153,254/year)
  • Better top-earner potential ($170,158)
  • Larger job market (2,260 employed)
  • Better purchasing power (CoL-adjusted: $161,804)
  • You prefer the Texas area and lifestyle

Choose Tyler if…

  • You prefer the Texas area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, pharmacist salaries in San Antonio grew 17.5% from 2019 to 2025, compared to -0.5% growth in Tyler over the same period.

San Antonio, TX

+17.5%

$128,080 (2019) → $150,500 (2025)

Tyler, TX

+-0.5%

$137,440 (2019) → $136,790 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays pharmacists more: San Antonio or Tyler?

San Antonio has a higher median pharmacist salary at $153,254/year, compared to Tyler at $139,293/year — a difference of $13,961 (10.02%).

What is the hourly rate difference between San Antonio and Tyler?

San Antonio pharmacists earn $73.68/hr while Tyler hygienists earn $66.96/hr (2026 est.).

Should I relocate from San Antonio to Tyler as a pharmacist?

Consider more than just salary when comparing San Antonio and Tyler. Factor in cost of living (CoL-adjusted: San Antonio = $161,804, Tyler = $151,149), job availability (2,260 vs 280 employed), commute, and career growth potential.

What do entry-level pharmacists earn in San Antonio vs Tyler?

Entry-level (10th percentile) pharmacists earn $98,439 in San Antonio and $106,311 in Tyler. The Tyler area offers higher starting salaries.

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Written by Sofia Chen, PharmD

Career Analyst

Sofia Chen has 10 years of experience in community pharmacy. She specializes in medication therapy management.

Clinically reviewed by Liam Patel, PharmDData verified by Amina Al-Sayed, PharmD

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 1.83% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Sofia Chen, PharmD, a licensed pharmacist with 10+ years of clinical experience. · View source data at BLS.gov