Pharmacist Salary

San Francisco vs San Marcos: Pharmacist Salary (2026)

Compare pharmacist salaries between San Francisco, CA and San Marcos, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$180,657
$86.85/hr
San Marcos, CA
$165,471
$79.55/hr

Side-by-Side Comparison

MetricSan Francisco, CASan Marcos, CA
Median Salary$180,657$165,471
Hourly Rate$86.85$79.55
Entry Level (P10)$138,061$112,540
25th Percentile$167,571$148,159
75th Percentile$224,148$189,103
Top Earner (P90)$233,415$212,316
Total Employed3,67017
Side-by-side bar chart comparing San Francisco ($180,657) and San Marcos ($165,471) pharmacist salaries.San FranciscoSan MarcosMedian Salary$180,657$165,471Entry Level (P10)$138,061$112,540Top Earner (P90)$233,415$212,316US Median $143,489

Verdict

San Francisco, CA offers better overall compensation for pharmacists, winning 4 out of 4 metrics compared to San Marcos.

The salary gap between San Francisco and San Marcos is $15,186 (9.18%). San Francisco's median is +25.90% compared to the US national median of $143,489.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $95,354,San Marcos spans $99,776. San Marcos has a wider pay range, suggesting more variation in pay between entry-level and experienced pharmacists.

San Francisco
P10 (Entry)$138,061
P25$167,571
Median$180,657
P75$224,148
P90 (Top)$233,415
San Marcos
P10 (Entry)$112,540
P25$148,159
Median$165,471
P75$189,103
P90 (Top)$212,316

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($156,260 effective) pays 6.80% more than San Marcos ($146,305 effective).

San Francisco
Nominal: $180,657
CoL Index: 115.613
Adjusted: $156,260
San Marcos
Nominal: $165,471
CoL Index: 113.1
Adjusted: $146,305

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($180,657/year)
  • Better top-earner potential ($233,415)
  • Larger job market (3,670 employed)
  • Better purchasing power (CoL-adjusted: $156,260)
  • You prefer the California area and lifestyle

Choose San Marcos if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, pharmacist salaries in San Francisco grew 15.3% from 2019 to 2025, compared to -8.5% growth in San Marcos over the same period.

San Francisco, CA

+15.3%

$153,870 (2019) → $177,410 (2025)

San Marcos, CA

+-8.5%

$177,542 (2024) → $162,497 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays pharmacists more: San Francisco or San Marcos?

San Francisco has a higher median pharmacist salary at $180,657/year, compared to San Marcos at $165,471/year — a difference of $15,186 (9.18%).

What is the hourly rate difference between San Francisco and San Marcos?

San Francisco pharmacists earn $86.85/hr while San Marcos hygienists earn $79.55/hr (2026 est.).

Should I relocate from San Francisco to San Marcos as a pharmacist?

Consider more than just salary when comparing San Francisco and San Marcos. Factor in cost of living (CoL-adjusted: San Francisco = $156,260, San Marcos = $146,305), job availability (3,670 vs 17 employed), commute, and career growth potential.

What do entry-level pharmacists earn in San Francisco vs San Marcos?

Entry-level (10th percentile) pharmacists earn $138,061 in San Francisco and $112,540 in San Marcos. The San Francisco area offers higher starting salaries.

Related Comparisons

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Written by Sofia Chen, PharmD

Career Analyst

Sofia Chen has 10 years of experience in community pharmacy. She specializes in medication therapy management.

Clinically reviewed by Liam Patel, PharmDData verified by Amina Al-Sayed, PharmD

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 1.83% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Sofia Chen, PharmD, a licensed pharmacist with 10+ years of clinical experience. · View source data at BLS.gov